Final solution if you can't open Windows Settings in Windows 10

I had this issue some weeks ago and I have seen plenty of possible solutions on the internet. Some of them even guide you through the Windows register.

In my case, the problem was caused by a faulty installation of a Windows Update (in my case it was the update KB5022906).

If you have this problem and tried several solutions without success, here's one more for you to try:

1. Go to the Microsoft Update Catalog (https://www.catalog.update.microsoft.com/Home.aspx)
2. Search for the Windows Update that you faced the problem by its KB reference.
3. Run the Microsoft Installer file downloaded.

If you have a similar issue as me, this should solver this problem and after the Windows Update installation you'll be able to open again the Windows Settings.